Article
ROP-Screening Results Cologne 2001–2008
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Published: | June 29, 2009 |
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Purpose: This study aims to evaluate results of retinopathy of prematurity (ROP) screening at the University Hospital of Cologne from 2001 to 2008.
Methods: Screening was performed according to german guidelines: prematures born at gestational age (GA) less than 32 weeks or birth weight (BW) less than 1500 grams required screening. Extended guideline included prematures with GA 32–36 weeks and more than three days of oxygen treatment. Laser coagulation (LC) treatment was performed upon threshold criteria. Data was analyzed for incidence and stage of ROP and necessity of treatment.
Results: 657 patients required screening between 07/2001 and 12/2008. 584 (88.9%) of infants were diagnosed with either no ROP, stage I or II. Retrospective analysis did not allow subclassification of stages 0-II. Sub-threshold stage III developed in 25 (3.8%). Average GA was 28.0 (+/-2.7) weeks, average BW was 1045 (+/-371) grams. LC became necessary in 48 (7.3%). 3 patients required re-LC. Average GA and BW of treated patients was 24.7 (+/-1.6) weeks and 621 (+/-205) grams, respectively.
Conclusions: In this cohort, all patients requiring treatment were detected in time with regard to german guidelines, and were treated sufficiently with LC. Relative risk of treatment necessity correlated significantly with lower GA and BW. Treatment was not indicated in any premature GA more than 29 weeks, or BW more than 1300 grams.