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28. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung (DAV 2010)

13.01. bis 16.01.2010, Schladming, Österreich

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Spray vs. Folie – Prävention von hypertropher Narbenbildung mit Silikon und Kompression

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  • corresponding author Lars Steinsträßer - BG Universitätskliniken Bergmannsheil, Plastische Chirurgie, Bochum, Deutschland
  • E. Flak - BG Universitätskliniken Bergmannsheil, Plastische Chirurgie, Bochum, Deutschland
  • S. Al-Benna - BG Universitätskliniken Bergmannsheil, Plastische Chirurgie, Bochum, Deutschland
  • B. Witte - BG Universitätskliniken Bergmannsheil, Plastische Chirurgie, Bochum, Deutschland
  • T. Hirsch - BG Universitätskliniken Bergmannsheil, Plastische Chirurgie, Bochum, Deutschland
  • H. U. Steinau - BG Universitätskliniken Bergmannsheil, Plastische Chirurgie, Bochum, Deutschland

DAV 2010. 28. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Verbrennungsbehandlung. Schladming, Österreich, 13.-16.01.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. Doc10dav49

doi: 10.3205/10dav49, urn:nbn:de:0183-10dav493

Published: June 30, 2010

© 2010 Steinsträßer et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

Text

Introduction: Prevention of hypertophic scars and keloids in burned patients are still problematic The combination of compression therapy and silicone sheets is a promising method of Prevention. In this randomized long-term study the efficacy of a new topical self drying silicone preparation in the prevention of hypertrophic scars and keloids combined with compression therapy has been assessed and compared to a control treatment composed of silicone sheeting and compression in split thickness graft burn wounds.

Methods: 40 patients with two comparable areas of split thickness graft burn wounds (wounds sized at least 3 cm x 5 cm each, burn index <100) have been included into this study.

Study design: Open, single-center, randomized controlled study, intra-individual comparison of study preparation and control to standard treatment. Right after split thickness skin grafts were adherent Patients received compression garments and were randomized to two of the following treatment groups a) Self Drying Silicone Spray (Kelocote) b) Silicone Sheeting (Mepithel) or c) no treatment contr ol. Clinical assessment by scores (Vancouver Scar Scale), measurement of scar redness (Chromametry) and height (Profilometry) photo documentation of each treated area are performed at different visits with a long-term follow-up of 18 months.

Results: The results of this study (40/40 Patient finished the 18 months follow-up) indicate that the efficacy of Self Drying Silicone Spray appears comparable to silicone gel sheeting. The patients' satisfaction and compliance are higher in the silicone Spray group compared to silicone sheeting.

Conclusion: This study shows first evidence that the results with Self Drying Silicone-Spray treatment are comparable with the current clinical gold standard of silicone sheeting. In contrast to the Silicone Sheeting, Self Drying Silicone Spray can be applied easier on uneven and widespread scar areas without touching the wound, the silicone spray layer cannot shift and the procedure of fixing and cleaning of the sheets will be avoided. An advantage.