Article
Inverted papilloma of the nose and paranasal sinuses: retrospective review of 110 cases
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Published: | July 6, 2010 |
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An inverted papilloma (IP) is a rare benign tumor of the nasal cavity and paranasal sinuses, which can be locally aggressive and has a tendency to recur and a malignant potential.
In this clinical study, 110 patients (age 15 to 82 years (53.4+13.6)) with the diagnosis IP, which were treated from 1990 to 2000 in our department, were analysed retrospectively to define sex, tumor location and method of treatment in correlation to the recurrence free time and postoperative complication rate.
Involvement of the maxillary sinus was observed in 50% of patients. In 90% the IP was located unilaterally. In all cases primary surgical resection of IP was performed. A recurrence occurred in 18.2% of patients. No statistically significant correlation was observed between sex, tumor location and treatment technique correlated to the recurrence free time. Association with malignancy was observed in 3.6% of cases. Patients treated with an extranasal technique or a combination of endo- and extranasal technique showed statistically significant more sinusitis (p=0.014), nasal crusting (p=0.027) and paresthesia of the skin (p=0.01). The latest recurrence occurred 8 years after resection of the IP.
We conclude that, if the tumor has adequate size and location, primary endoscopic technique should be preferred to extranasal techniques because of less postoperative complication rates. Regarding the recurrence free interval, the endonasal technique provides no disadvantage compared to other techniques. A longterm postoperative follow up should be performed due to the risk of late recurrences.