Article
Sialendoscopy and intraductal application of prednisone as a symptomatical treatment of Sjoegren`s disease
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Authors
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Stephan Krämer
- HNO-Kath Klinikum Marienhof, Koblenz, Germany
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Andreas Glowania
- HNO Praxis Prof Klimmek, Wiesbaden, Germany
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Jan Maurer
- HNO-Kath Klinikum Marienhof, Koblenz, Germany
| Published: | July 6, 2010 |
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Outline
Text
Introduction: Morbus Sjoegren is an idiopathic autoimmune disease. Therapy is symptomatic. Patients wirth Sjoegren`s disease are often treated by otolaryngologists because of sialadenopathy of the salivary glands and dryness of the oral mucosa.
Method: A unilateral superficial parotidectomy was performed on a patient with recurrent sialadenopathy of the parotid glands. However symptoms continued postoperatively. Histology was benign. Afte the diagnosis of uveitis was confirmed, Sjoegren`s disease was suggested. Biopsy of the oral mucosa confirmed the diagnosis of Sjoegren`s disease. A sialendoscopy of the parotid glands was then performed due to treatment failure with previous procedures.
Material and results: The sialendoscopy showed inflammation of the stenon ducts without any lobe atrophy. The ducts were then flushed with prednisone solution. The parotid glands were temporarily swollen postoperatively for a period of 24 hours. After that the patient was free of symptoms for the last 6 months.
Conclusions: Intraductal application of prednisone seems to be an alternative symptomatic treatment of Sjoegren`s disease with similar results as in the treatment of postradiogenic sialadenosis of the parotid glands.
References
- 1.
- Beutner S, Meyer E. Sialendoskopie bei 24 Patienten bei postradiogenen Sialadenosen. HNO. 2009;12:347- 352.
