gms | German Medical Science

23rd Annual Meeting of the German Retina Society

German Retina Society

24.09. - 25.09.2010, Freiburg

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Objective functional long-term improvement following photodynamic therapy in circumscribed choroidal hemangioma

Meeting Abstract

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  • Bernhard Jurklies - University Eye Clinic Essen
  • A. Lipski - University Eye Clinic Essen

German Retina Society. 23rd Annual Conference of the German Retina Society. Freiburg i. Br., 24.-25.09.2010. Düsseldorf: German Medical Science GMS Publishing House; 2010. Doc10rg34

doi: 10.3205/10rg34, urn:nbn:de:0183-10rg344

This is the English version of the article.
The German version can be found at: http://www.egms.de/de/meetings/rg2010/10rg34.shtml

Published: September 21, 2010

© 2010 Jurklies et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Purpose: To objectively investigate retinal function using multifocal electroretinography in patients with choroidal hemangioma undergoing treatment with photodynamic therapy using verteporfin (PDT).

Method: 8 eyes of 8 patients with vision loss due to subfoveal exudation related to choroidal hemangioma underwent photodynamic therapy (light dose of 100 J/m² at 692 nm). Pre- and postinterventional conduction of 103 focal ERGs in the central 25° was performed using the VERIS multifocal electroretinography system (mfERG, EDI, California). Follow-up examinations were performed after 60–82 months.

Results: Central amplitudes of N1 and P1 mfERG responses revealed early increases with shortened implicit times corresponding to fluid resorption and vision gain after PDT.

Conclusion: mfERG long-term follow-up reveals sustainment after early improvement of retinal function and further underlines PDT efficacy and safety in patients with symptomatic circumscribed choroidal hemangioma.