Article
Comparison of health-related quality of life after heart or lung transplantation between patients with prolonged and short postoperative intensive care unit stay
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Published: | May 20, 2011 |
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Introduction: Heart and lung transplantation might be followed by a complicated post-operative course with prolonged intensive medical care (ICU) and unclear outcome. Otherwise several patients stayed short-term on ICU. Therefore the aim of the retrospective study is a comparison of health-related quality of life (HRQOL) between patients with prolonged and short ICU stay.
Materials and methods: A retrospective analysis of 74 patients operated on heart or lung transplantation between 1988 and 2008 was performed. Patients with 5 days or less and with 14 days or more on ICU, which are still alive, were included and analyzed by questionnaires (SF-36). 42 patients took part. Rate of return was 56%.
Results: Patients with prolonged and short ICU stay were almost equivalent in age (56+/-13.2y vs. 52.5+/-11.3y), gender (87% male vs. 68.4%, 13% female vs. 31.6%), proportion of thoracic transplantation (lung transplantation 73.9% vs. 78.9%, heart transplantation 26.1% vs. 21.1%) and follow up period (55.2+/-46.4 months vs. 44.6+/-16.6 months). Mean ICU stay (34+/-21.2 days vs. 3.5+/-1.3 days, p=0) and ventilation time (227.8+/-57.9 hours vs. 30.6+/-17 hours, p=0.04) were significant different. Recipients with prolonged ICU stay showed a significant reduced mental HRQOL (50.8+/-9.8 vs. 55.9+/-5.9, p=0.05), the physical HRQOL of the two groups were almost equivalent (prolonged ICU 45.7+/-13.1 vs. short ICU 46.9+/-11.4). In the follow up there was no significant difference of heart (ejection fraction: prolonged ICU 55.8%+/-8 vs. short ICU 63%+/-4) and lung function (forced expiratory volume in 1 second: prolonged ICU 76.6%+/-22 vs. short ICU 89.3%+/-23.8).
Conclusion: Prolonged ICU stay after heart or lung transplantation affects negatively the mental HRQOL, but physical HRQOL and constitution is almost equivalent.