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128. Kongress der Deutschen Gesellschaft für Chirurgie

Deutsche Gesellschaft für Chirurgie

03.05. - 06.05.2011, München

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Donor and Recipient Body Mass Index Correlate with Initial Kidney Graft Function

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  • Annemarie Weißenbacher - Medizinische Universität Innsbruck, Universitätsklinik für Visceral-, Transplantations- und Thoraxchirurgie, Innsbruck
  • Matthias Biebl - Medizinische Universität Innsbruck, Universitätsklinik für Visceral-, Transplantations- und Thoraxchirurgie, Innsbruck
  • Maximilian Jara - Medizinische Universität Innsbruck, Universitätsklinik für Visceral-, Transplantations- und Thoraxchirurgie, Innsbruck
  • Claudia Bösmüller - Medizinische Universität Innsbruck, Universitätsklinik für Visceral-, Transplantations- und Thoraxchirurgie, Innsbruck
  • Johann Pratschke - Medizinische Universität Innsbruck, Universitätsklinik für Visceral-, Transplantations- und Thoraxchirurgie, Innsbruck
  • Robert Öllinger - Medizinische Universität Innsbruck, Universitätsklinik für Visceral-, Transplantations- und Thoraxchirurgie, Innsbruck

Deutsche Gesellschaft für Chirurgie. 128. Kongress der Deutschen Gesellschaft für Chirurgie. München, 03.-06.05.2011. Düsseldorf: German Medical Science GMS Publishing House; 2011. Doc11dgch569

doi: 10.3205/11dgch569, urn:nbn:de:0183-11dgch5694

Published: May 20, 2011

© 2011 Weißenbacher et al.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited.

Outline

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Introduction: Obesity is a worldwide epidemic. The number of overweight renal transplant recipients and cadaveric donors is increasing. We investigated whether donor and/or recipient body mass index correlate with the occurrence of delayed graft function after kidney transplantation.

Materials and methods: Retrospective analysis of 708 consecutive cadaveric kidney transplants between January 2003 and December 2009. Delayed graft function was defined as requirement for more than one dialysis post-transplant dialysis. Impact of body mass index, gender, age, re-transplant, cold ischemia and anastomosis time on the occurrence of delayed graft function were analyzed using uni- and multivariate analyses.

Results: DGF rate was 25,2%, 29.8%, 40,9% and 52,6% in recipients with a body mass index <20, 20-25, 25-30 and >30kg/m2 respectively (p=0,0002). Donor body mass index <20, 20-25, 25-30 and >30kg/m2 resulted in a DGF rate of 22,5%, 31,0%, 37,3% and 51,2% (p<0,0001). Multivariate analysis revealed overweight in the recipient as well as in the donor as an independent risk factor for delayed graft function.

Conclusion: Donor as well as recipient body mass index correlate with the incidence of delayed graft function.