gms | German Medical Science

Background: It is advisable searching and evaluating published clinical practice guidelines (CPG) before the development of de novo guideline. It is important to evaluate the possibility of implementation of recommendations of CPG; eGLIA tool is useful for evaluating the intrinsic barriers of the adaptation of GPC. Before developing a CPG of diarrhea in children, we evaluated the best available guidelines on the topic.

Objective: To evaluate the applicability of eGLIA in evaluating diarrea CPG susceptible to adaptation. To assess the perception of eGLIA from evaluators.

Methods: We evaluated the best 6 CPG of diarrhea according to the AGREE-II instrument. eGLIA for 4 was used in CPG trained evaluators. Online version was used, following recommendations of authors. Perception was investigated using the instrument.

Results: Four evaluators completed eGLIA. All CPG had difficulties in at least one of the domains of eGLIA. A guide had barriers in 4 domains. There was borderline evaluation in 2 domains. We were unable to assess the domain computability. The perception of the instrument showed difficulties in the use of eGLIA.

Discussion: eGLIA didn't discriminate in the selection of adaptable CPG. Domains are not clear for the selection. Computability domain is not assessable for the selection of a CPG to adapt. eGLIA use was considered difficult. Several domains have been previously evaluated by the AGREE-II.

Implications: We do not recommend eGLIA in the process of selecting adaptive CPG. Authors are encouraged to summarize the questions of the domains.